R 039 Pill — YELLOW RECTANGLE, 15mm — Alprazolam

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ImprintR / 039
ColourYELLOW
ShapeRECTANGLE
Size15
StrengthALPRAZOLAM 2 mg
Dosage formTablet
ManufacturerActavis Pharma, Inc.
NDC0228-2039
ScheduleCIV
AvailabilityDrug For Further Processing
IngredientsALPRAZOLAM[ALPRAZOLAM]

What does this imprint mean?

The imprint "R 039" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.

Active ingredient

Alprazolam

Uses and warnings

Key warnings include: - Dependence/Withdrawal: "Certain adverse clinical events, some life-threatening, are a direct consequence of physical dependence." Even at recommended doses, dependence risk exists; risk increases above 4 mg/day. Seizures can occur during discontinuation. - CNS Depression: Patients should avoid "hazardous occupations or activities requiring complete mental alertness such as operating machinery or driving." - Pregnancy: Benzodiazepines "potentially cause fetal harm when administered to pregnant women"; avoid during first trimester. - CYP3A Interactions: Contraindicated with ketoconazole and itraconazole due to dangerous metabolic interactions. ---

Alprazolam tablets treat two primary conditions: Anxiety Disorders: "management of anxiety disorder" corresponding to generalized anxiety disorder, or "short-term relief of symptoms of anxiety." The label specifies that everyday stress-related anxiety typically doesn't warrant treatment. Panic Disorder: "treatment of panic disorder, with or without agoraphobia." Clinical studies demonstrated effectiveness over 4-10 weeks, though some patients received treatment up to 8 months without apparent loss of benefit. ---

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Official references

Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file 84ebf58b-deef-4f35-ba5e-e901288c2997.xml