MYLAN 451 Pill — WHITE OVAL, 16mm — Naproxen
| Imprint | MYLAN / 451 |
|---|---|
| Colour | WHITE |
| Shape | OVAL |
| Size | 16 |
| Strength | NAPROXEN 500 mg |
| Dosage form | Tablet |
| Manufacturer | Mylan Pharmaceuticals Inc. |
| NDC | 0378-0451 |
| Schedule | — |
| Availability | — |
| Ingredients | NAPROXEN[NAPROXEN] |
What does this imprint mean?
The imprint "MYLAN 451" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.
Active ingredient
Naproxen
Uses and warnings
BOXED WARNING: Boxed Warning - Cardiovascular & GI Risk: NSAIDs increase risk of serious cardiovascular thrombotic events (myocardial infarction, stroke) that can be fatal, potentially early in treatment. They also cause increased risk of serious gastrointestinal bleeding, ulceration, and perforation, which can occur without warning symptoms. Key Warnings Include: - Contraindicated after coronary artery bypass graft surgery - "Patients with a prior history of peptic ulcer disease...had a greater than 10-fold increased risk for developing a GI bleed" - Risk of hepatotoxicity, hypertension, heart failure, renal toxicity, anaphylactic reactions, serious skin reactions, and hematologic toxicity - Avoid in pregnant women starting at 30 weeks gestation due to fetal ductus arteriosus closure risk
Naproxen sodium tablets treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and juvenile arthritis. They also relieve tendonitis, bursitis, acute gout, pain, and primary dysmenorrhea. "Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals."
How to identify this pill
- • Check the imprint matches exactly: "MYLAN 451".
- • Confirm the colour (WHITE) and shape (OVAL).
- • Compare the size (16) against a ruler if possible.
- • When in doubt, confirm with a pharmacist before taking any medication.
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Official references
Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file 71b8147a-aabc-43a4-8285-cb22d8619854.xml