M 146 Pill — WHITE ROUND, 9mm — Spironolactone
| Imprint | M / 146 |
|---|---|
| Colour | WHITE |
| Shape | ROUND |
| Size | 9 |
| Strength | SPIRONOLACTONE 25 mg |
| Dosage form | Tablet, Film Coated |
| Manufacturer | Aphena Pharma Solutions - Tennessee, LLC |
| NDC | 67544-310 |
| Schedule | — |
| Availability | Prescription only |
| Ingredients | SPIRONOLACTONE[SPIRONOLACTONE] |
What does this imprint mean?
The imprint "M 146" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.
Active ingredient
Spironolactone
Uses and warnings
No boxed warning. Contraindications include hyperkalemia, Addison's disease, and concomitant use with eplerenone. Key warnings include hyperkalemia, which can be serious or fatal, requiring potassium monitoring "within the first week" of therapy and periodically thereafter, especially with ACE inhibitors, ARBs, or potassium supplements; risk of hypotension and acute worsening of renal function; electrolyte disturbances such as hyponatremia; and tumorigenicity noted in chronic animal toxicity studies.
Spironolactone is indicated for management of NYHA Class III-IV heart failure with reduced ejection fraction, to increase survival and manage edema, generally combined with other heart-failure therapies; management of hypertension as add-on therapy when other agents are inadequate; management of edema in cirrhosis of the liver when fluid/sodium restriction alone is ineffective; treatment of edema of nephrotic syndrome when other therapies are inadequate; and short-term preoperative treatment or long-term maintenance therapy for primary hyperaldosteronism.
How to identify this pill
- • Check the imprint matches exactly: "M 146".
- • Confirm the colour (WHITE) and shape (ROUND).
- • Compare the size (9) against a ruler if possible.
- • When in doubt, confirm with a pharmacist before taking any medication.
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Official references
Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file a09954f9-6bcf-4082-a363-406c4a4646e6.xml