M 318 Pill — WHITE ROUND, 10mm — Pioglitazone
| Imprint | M / 318 |
|---|---|
| Colour | WHITE |
| Shape | ROUND |
| Size | 10 |
| Strength | PIOGLITAZONE HYDROCHLORIDE 45 mg |
| Dosage form | Tablet |
| Manufacturer | Mylan Institutional Inc. |
| NDC | 51079-515 |
| Schedule | — |
| Availability | — |
| Ingredients | PIOGLITAZONE HYDROCHLORIDE[PIOGLITAZONE] |
What does this imprint mean?
The imprint "M 318" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.
Active ingredient
Pioglitazone
Uses and warnings
BOXED WARNING: "CONGESTIVE HEART FAILURE - Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart failure in some patients." Patients should be observed for "signs and symptoms of heart failure (including excessive, rapid weight gain, dyspnea, and/or edema)," and "initiation of ACTOS in patients with established NYHA Class III or IV heart failure is contraindicated." Other key warnings include bladder cancer risk ("16/3656 (0.44%)" reports with pioglitazone vs. "5/3679 (0.14%)" without), increased bone fracture incidence in women (5.1% vs. 2.5% on placebo), and fluid retention that "may lead to or exacerbate heart failure."
ACTOS is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
How to identify this pill
- • Check the imprint matches exactly: "M 318".
- • Confirm the colour (WHITE) and shape (ROUND).
- • Compare the size (10) against a ruler if possible.
- • When in doubt, confirm with a pharmacist before taking any medication.
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Official references
Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file 7d7c9874-0673-255a-e053-2991aa0ab6ca.xml