M Pill — ORANGE ROUND, 6mm — Estradiol

Imprint	M
Colour	ORANGE
Shape	ROUND
Size	6
Strength	LEVOMEFOLATE CALCIUM 0.451 mg
Dosage form	Tablet, Film Coated
Manufacturer	Sandoz Inc
NDC	0781-4103
Schedule	—
Availability	Prescription only
Ingredients	LEVOMEFOLATE CALCIUM[LEVOMEFOLIC ACID]

What does this imprint mean?

The imprint "M" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.

Active ingredient

Estradiol

Uses and warnings

BOXED WARNING: "ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER" in women with a uterus, with risk related to dose and duration of use; "close clinical surveillance of all women taking estrogens is important." The label also states "estrogens with or without progestins should not be used for the prevention of cardiovascular disease," citing Women's Health Initiative findings of "increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis" and an increased risk of dementia in women 65 and older. Contraindications include undiagnosed abnormal genital bleeding, known or suspected breast cancer, active or history of DVT/PE or arterial thromboembolic disease, liver dysfunction, known or suspected pregnancy, and known hypersensitivity.

Indicated for treatment of moderate to severe vasomotor symptoms (hot flashes) and moderate to severe vulvar and vaginal atrophy associated with menopause; treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure; palliative treatment of certain cases of metastatic breast cancer and advanced androgen-dependent prostate cancer; and prevention of postmenopausal osteoporosis.

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How to identify this pill

• Check the imprint matches exactly: "M".
• Confirm the colour (ORANGE) and shape (ROUND).
• Compare the size (6) against a ruler if possible.
• When in doubt, confirm with a pharmacist before taking any medication.

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