Lotrel 0379 Pill — BLUE CAPSULE, 19mm — Amlodipine

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ImprintLotrel / 0379
ColourBLUE
ShapeCAPSULE
Size19
Strengthamlodipine besylate 10 mg;benazepril hydrochloride 40 mg
Dosage formCapsule
ManufacturerCardinal Health
NDC55154-9668
Schedule—
Availability—
Ingredientsamlodipine besylate[amlodipine];benazepril hydrochloride[benazepril]

What does this imprint mean?

The imprint "Lotrel 0379" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.

Active ingredient

Amlodipine

Uses and warnings

Key warnings include symptomatic hypotension risk, particularly in severe aortic stenosis patients. "Worsening angina and acute myocardial infarction can develop after starting or increasing the dose," especially in severe obstructive coronary artery disease cases. Hepatic impairment requires slower titration due to extended elimination half-life (56 hours).

Amlodipine besylate treats hypertension and coronary artery disease conditions. For high blood pressure, it "lower[s] blood pressure" to reduce cardiovascular event risk. For heart disease, it addresses chronic stable angina, vasospastic angina, and documented CAD in patients without heart failure or ejection fraction below 40%. The medication may be used alone or combined with other agents.

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Official references

Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file e11652b8-6ce6-4366-9519-a43a0d36f235.xml