AP 12 Pill — RED ROUND, 9mm — Pioglitazone

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Imprint	AP / 12
Colour	RED
Shape	ROUND
Size	9
Strength	ALOGLIPTIN BENZOATE 12.5 mg;PIOGLITAZONE HYDROCHLORIDE 45 mg
Dosage form	Tablet, Film Coated
Manufacturer	Takeda Pharmaceuticals America, Inc.
NDC	64764-124
Schedule	—
Availability	—
Ingredients	ALOGLIPTIN BENZOATE[ALOGLIPTIN];PIOGLITAZONE HYDROCHLORIDE[PIOGLITAZONE]

What does this imprint mean?

The imprint "AP 12" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.

Active ingredient

Pioglitazone

Uses and warnings

BOXED WARNING: "CONGESTIVE HEART FAILURE - Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart failure in some patients." Patients should be observed for "signs and symptoms of heart failure (including excessive, rapid weight gain, dyspnea, and/or edema)," and "initiation of ACTOS in patients with established NYHA Class III or IV heart failure is contraindicated." Other key warnings include bladder cancer risk ("16/3656 (0.44%)" reports with pioglitazone vs. "5/3679 (0.14%)" without), increased bone fracture incidence in women (5.1% vs. 2.5% on placebo), and fluid retention that "may lead to or exacerbate heart failure."

ACTOS is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Read the full drug profile →

How to identify this pill

• Check the imprint matches exactly: "AP 12".
• Confirm the colour (RED) and shape (ROUND).
• Compare the size (9) against a ruler if possible.
• When in doubt, confirm with a pharmacist before taking any medication.

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