457 Pill — BROWN ROUND, 8mm — Amlodipine
| Imprint | 457 |
|---|---|
| Colour | BROWN |
| Shape | ROUND |
| Size | 8 |
| Strength | AMLODIPINE BESYLATE 10 mg;OLMESARTAN MEDOXOMIL 40 mg |
| Dosage form | Tablet, Film Coated |
| Manufacturer | Alembic Pharmaceuticals Inc. |
| NDC | 62332-215 |
| Schedule | — |
| Availability | Prescription only |
| Ingredients | AMLODIPINE BESYLATE[AMLODIPINE];OLMESARTAN MEDOXOMIL[OLMESARTAN] |
What does this imprint mean?
The imprint "457" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.
Active ingredient
Amlodipine
Uses and warnings
Key warnings include symptomatic hypotension risk, particularly in severe aortic stenosis patients. "Worsening angina and acute myocardial infarction can develop after starting or increasing the dose," especially in severe obstructive coronary artery disease cases. Hepatic impairment requires slower titration due to extended elimination half-life (56 hours).
Amlodipine besylate treats hypertension and coronary artery disease conditions. For high blood pressure, it "lower[s] blood pressure" to reduce cardiovascular event risk. For heart disease, it addresses chronic stable angina, vasospastic angina, and documented CAD in patients without heart failure or ejection fraction below 40%. The medication may be used alone or combined with other agents.
How to identify this pill
- • Check the imprint matches exactly: "457".
- • Confirm the colour (BROWN) and shape (ROUND).
- • Compare the size (8) against a ruler if possible.
- • When in doubt, confirm with a pharmacist before taking any medication.
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Official references
Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file c3a1177d-0c02-45ed-859d-76f7fefeeb28.xml