445 Pill — YELLOW ROUND, 9mm — Donepezil
| Imprint | 445 |
|---|---|
| Colour | YELLOW |
| Shape | ROUND |
| Size | 9 |
| Strength | DONEPEZIL HYDROCHLORIDE 10 mg |
| Dosage form | Tablet, Film Coated |
| Manufacturer | PD-Rx Pharmaceuticals, Inc. |
| NDC | 43063-500 |
| Schedule | — |
| Availability | — |
| Ingredients | DONEPEZIL HYDROCHLORIDE[DONEPEZIL] |
What does this imprint mean?
The imprint "445" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.
Active ingredient
Donepezil
Uses and warnings
Contraindicated in patients with "known hypersensitivity to donepezil hydrochloride or to piperidine derivatives." Key warnings: as a cholinesterase inhibitor, it is "likely to exaggerate succinylcholine-type muscle relaxation during anesthesia"; may have "vagotonic effects on the sinoatrial and atrioventricular nodes manifesting as bradycardia or heart block"; "ARICEPT can cause vomiting," with an associated risk of gastrointestinal bleeding, particularly at higher doses; weight loss has been reported with the 23 mg dose; potential to cause seizures in susceptible patients.
ARICEPT (donepezil hydrochloride) "is indicated for the treatment of dementia of the Alzheimer's type. Efficacy has been demonstrated in patients with mild, moderate, and severe Alzheimer's disease."
How to identify this pill
- • Check the imprint matches exactly: "445".
- • Confirm the colour (YELLOW) and shape (ROUND).
- • Compare the size (9) against a ruler if possible.
- • When in doubt, confirm with a pharmacist before taking any medication.
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Official references
Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file fb61aeff-d8f4-4423-9a0e-e9f1f2b3f7d5.xml