428 Pill — ORANGE ROUND, 6mm — Hydrochlorothiazide
| Imprint | 428 |
|---|---|
| Colour | ORANGE |
| Shape | ROUND |
| Size | 6 |
| Strength | — |
| Dosage form | Tablet |
| Manufacturer | CARACO PHARMACEUTICAL LABORATORIES, LTD. |
| NDC | 57664-428 |
| Schedule | — |
| Availability | — |
| Ingredients | — |
What does this imprint mean?
The imprint "428" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.
Active ingredient
Hydrochlorothiazide
Uses and warnings
Key warnings include: - "Use with caution in severe renal disease" as thiazides may precipitate azotemia - Caution advised with impaired hepatic function due to risk of hepatic coma - Risk of systemic lupus erythematosus exacerbation reported - "Lithium generally should not be given with diuretics" due to toxicity risk - Potential electrolyte imbalances requiring monitoring (hypokalemia, hyponatremia, hypochloremic alkalosis)
Hydrochlorothiazide is indicated for edema management associated with congestive heart failure, hepatic cirrhosis, and corticosteroid/estrogen therapy, as well as edema from renal dysfunction. It's also used to manage hypertension "either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs."
How to identify this pill
- • Check the imprint matches exactly: "428".
- • Confirm the colour (ORANGE) and shape (ROUND).
- • Compare the size (6) against a ruler if possible.
- • When in doubt, confirm with a pharmacist before taking any medication.
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Official references
Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file 7b38ac8a-4540-4eb2-aedd-9aa966d22190.xml