30 4 Pill — WHITE ROUND, 9mm — Pioglitazone

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Imprint30 / 4
ColourWHITE
ShapeROUND
Size9
Strengthpioglitazone hydrochloride 30 mg;glimepiride 4 mg
Dosage formTablet
ManufacturerPrasco Laboratories
NDC66993-822
Schedule—
AvailabilityPrescription only
Ingredientspioglitazone hydrochloride[pioglitazone];glimepiride[glimepiride]

What does this imprint mean?

The imprint "30 4" is a code stamped or printed on the tablet or capsule by the manufacturer, used to identify the drug, its strength and the maker.

Active ingredient

Pioglitazone

Uses and warnings

BOXED WARNING: "CONGESTIVE HEART FAILURE - Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart failure in some patients." Patients should be observed for "signs and symptoms of heart failure (including excessive, rapid weight gain, dyspnea, and/or edema)," and "initiation of ACTOS in patients with established NYHA Class III or IV heart failure is contraindicated." Other key warnings include bladder cancer risk ("16/3656 (0.44%)" reports with pioglitazone vs. "5/3679 (0.14%)" without), increased bone fracture incidence in women (5.1% vs. 2.5% on placebo), and fluid retention that "may lead to or exacerbate heart failure."

ACTOS is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

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Official references

Source: FDA Structured Product Label via NLM Pillbox archive (retired 2021); source file dff147fa-055f-4403-b3b0-dc00b273900b.xml