Verapamil

Brand names: CALAN, CALAN SR, Covera-HS, Tarka, Trandolapril and Verapamil Hydrochloride, VERAPAMIL HCL, VERAPAMIL HYDROCHLORIDE, VERELAN, VERELAN PM, Verapamil Hydrochloride, Verapamil hydrochloride, Verelan, verapamil hydrochloride

Warnings

No boxed warning. Contraindications include severe left ventricular dysfunction, hypotension (systolic BP <90 mmHg) or cardiogenic shock, sick sinus syndrome or second-/third-degree AV block without a pacemaker, and atrial fibrillation/flutter with an accessory bypass tract (e.g., WPW syndrome), where verapamil can paradoxically accelerate ventricular rate. Major warnings cover negative inotropic/chronotropic effects risking heart failure or bradycardia/AV block, elevated hepatic transaminases, and the need for caution in hepatic or renal impairment since verapamil's half-life is prolonged.

Uses

Verapamil Hydrochloride Tablets are indicated for management of vasospastic (Prinzmetal's variant) angina, unstable angina, and chronic stable angina; treatment of supraventricular tachyarrhythmias, including control of ventricular rate in atrial fibrillation or flutter and prevention of paroxysmal supraventricular tachycardia; and essential hypertension, to lower blood pressure, alone or in combination with other antihypertensives.

Dosage forms & strengths

Capsule, Delayed Release Pellets Capsule, Extended Release Tablet Tablet, Extended Release Tablet, Film Coated Tablet, Film Coated, Extended Release POWDER
TRANDOLAPRIL 1 mg VERAPAMIL HYDROCHLORIDE 240 mg TRANDOLAPRIL 2 mg VERAPAMIL HYDROCHLORIDE 180 mg TRANDOLAPRIL 4 mg VERAPAMIL HYDROCHLORIDE 100 mg VERAPAMIL HYDROCHLORIDE 120 mg VERAPAMIL HYDROCHLORIDE 200 mg VERAPAMIL HYDROCHLORIDE 300 mg VERAPAMIL HYDROCHLORIDE 360 mg VERAPAMIL HYDROCHLORIDE 40 mg VERAPAMIL HYDROCHLORIDE 80 mg trandolapril 2 mg verapamil hydrochloride 180 mg verapamil hydrochloride 240 mg trandolapril 4 mg verapamil hydrochloride 100 mg verapamil hydrochloride 120 mg verapamil hydrochloride 200 mg verapamil hydrochloride 300 mg verapamil hydrochloride 360 mg VERAPAMIL HYDROCHLORIDE 1 kg/kg

All identified pills

Side effects

Most frequently reported adverse reactions include constipation (7.3%), dizziness (3.3%), nausea (2.7%), hypotension (2.5%), headache (2.2%), edema (1.9%), and fatigue (1.7%). Serious adverse reactions include congestive heart failure or pulmonary edema (1.8%), symptomatic bradycardia below 50 bpm (1.4%), second- or third-degree AV block (1.2%), and hepatocellular injury.

Official source

DailyMed