Tramadol

Brand names: TRAMADOL HYDROCHLORIDE, Tramadol Hydrochloride, Tramadol Hydrochloride and Acetaminophen, Tramadol hydrochloride and acetaminophen, ULTRACET, Ultram ER, tramadol hydrochloride

Warnings

BOXED WARNING: Addiction/Abuse Risk - "exposes users to risks of addiction, abuse, and misuse, which can lead to overdose and death"; Respiratory Depression - "serious, life-threatening, or fatal respiratory depression may occur"; Accidental Ingestion - risk of fatal overdose, especially in children; contraindicated under age 12 and post-tonsillectomy under age 18; CNS Depressants - concomitant use with benzodiazepines may cause "profound sedation, respiratory depression, coma, and death."

Uses

"Management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate." Not for as-needed use; reserved for patients where non-opioid analgesics or immediate-release opioids prove ineffective or intolerable.

Dosage forms & strengths

Tablet Tablet, Coated Tablet, Extended Release Tablet, Film Coated
TRAMADOL HYDROCHLORIDE 100 mg TRAMADOL HYDROCHLORIDE 200 mg TRAMADOL HYDROCHLORIDE 300 mg TRAMADOL HYDROCHLORIDE 37.5 mg ACETAMINOPHEN 325 mg TRAMADOL HYDROCHLORIDE 50 mg tramadol hydrochloride 37.5 mg acetaminophen 325 mg

All identified pills

Side effects

Occurring in >=10% of patients at recommended doses: "dizziness, constipation, nausea, headache, somnolence, flushing, pruritus, vomiting, insomnia, and dry mouth." Additional reactions: respiratory depression, seizures, serotonin syndrome, hypotension, withdrawal symptoms.

Official source

DailyMed