Pravastatin
Brand names: PRAVACHOL, PRAVASTATIN SODIUM, Pravastatin Sodium, Pravastatin sodium, pravastatin sodium
Warnings
No boxed warning. Contraindications include "hypersensitivity to any component of this medication," "active liver disease or unexplained, persistent elevations of serum transaminases," and use during pregnancy and lactation. Key warnings cover skeletal muscle effects - patients should report "unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever" - with rare cases of "rhabdomyolysis with acute renal failure secondary to myoglobinuria," and rare immune-mediated necrotizing myopathy (IMNM) with "proximal muscle weakness and elevated serum creatine kinase, which persist despite discontinuation of statin treatment."
Uses
Pravastatin is indicated to reduce the risk of MI, revascularization, and cardiovascular mortality in hypercholesterolemic patients without clinically evident coronary heart disease, and in patients with existing coronary heart disease to reduce "the risk of total mortality by reducing coronary death, MI, revascularization, stroke/TIA, and the progression of coronary atherosclerosis." Also indicated as an adjunct to diet for elevated total cholesterol, LDL-C, and triglycerides, and for "heterozygous familial hypercholesterolemia" in pediatric patients 8 years and older who fail diet therapy.
Dosage forms & strengths
All identified pills
10 0013
PINK RECTANGLE · Pravastatin
20 0014
YELLOW RECTANGLE · Pravastatin
40 0016
GREEN RECTANGLE · Pravastatin
80 0019
YELLOW OVAL · Pravastatin
93 771
PINK ROUND · Pravastatin
2 manufacturers
93 7202
GREEN ROUND · Pravastatin
2 manufacturers
93 7201
YELLOW ROUND · Pravastatin
2 manufacturers
93 7270
WHITE OVAL · Pravastatin
AC 144
WHITE OVAL · Pravastatin
AC 141
WHITE RECTANGLE · Pravastatin
AC 142
WHITE RECTANGLE · Pravastatin
AC 143
WHITE RECTANGLE · Pravastatin
APO PRA
PINK ROUND · Pravastatin
14 manufacturers
APO PRA
GREEN ROUND · Pravastatin
20 manufacturers
APO PRA
WHITE ROUND · Pravastatin
APO PRA
YELLOW ROUND · Pravastatin
18 manufacturers
APO PRA
YELLOW ROUND · Pravastatin
8 manufacturers
BMS 80
YELLOW OVAL · Pravastatin
C183
YELLOW CAPSULE · Pravastatin
C184
YELLOW CAPSULE · Pravastatin
C185
YELLOW CAPSULE · Pravastatin
C186
YELLOW CAPSULE · Pravastatin
G5 10
YELLOW ROUND · Pravastatin
12 manufacturers
G5 80
YELLOW OVAL · Pravastatin
4 manufacturers
G5 40
GREEN RECTANGLE · Pravastatin
13 manufacturers
G5 20
YELLOW RECTANGLE · Pravastatin
14 manufacturers
HLP 10
BROWN ROUND · Pravastatin
2 manufacturers
HLP 20
BROWN ROUND · Pravastatin
3 manufacturers
HLP 40
BROWN ROUND · Pravastatin
2 manufacturers
HLP 80
BROWN OVAL · Pravastatin
3 manufacturers
HU 80
YELLOW OVAL · Pravastatin
HU 20
YELLOW RECTANGLE · Pravastatin
HU 40
YELLOW RECTANGLE · Pravastatin
LU N01
YELLOW CAPSULE · Pravastatin
2 manufacturers
LU N02
YELLOW CAPSULE · Pravastatin
5 manufacturers
LU N03
YELLOW CAPSULE · Pravastatin
LU N04
YELLOW OVAL · Pravastatin
P 14
PINK ROUND · Pravastatin
P 15
YELLOW ROUND · Pravastatin
P 16
BLUE ROUND · Pravastatin
P 18
ORANGE OVAL · Pravastatin
P Pravachol
GREEN RECTANGLE · Pravastatin
P Pravachol
YELLOW RECTANGLE · Pravastatin
PB 4
YELLOW OVAL · Pravastatin
5 manufacturers
PB 1
PINK RECTANGLE · Pravastatin
7 manufacturers
PB 8
GREEN RECTANGLE · Pravastatin
12 manufacturers
PB 2
YELLOW RECTANGLE · Pravastatin
10 manufacturers
PV 10
WHITE CAPSULE · Pravastatin
2 manufacturers
Side effects
In short-term trials, the most frequent reactions were "musculoskeletal pain, nausea/vomiting, upper respiratory infection, diarrhea, and headache." Long-term data reported musculoskeletal pain in 24.9% of patients, fatigue in 8.4%, and upper respiratory tract infection in 21.2%. Postmarketing reports include myopathy, rhabdomyolysis, tendon disorder, polymyositis, and rare cognitive impairment ("memory loss, forgetfulness, amnesia, memory impairment, confusion").