Phentermine
Brand names: Adipex-P, LOMAIRA, PHENTERMINE HCL, PHENTERMINE HCL C-IV, PHENTERMINE HYDROCHLORIDE, Phentermine HCl, Phentermine Hydrochloride, Phentermine Resin, Phentermine hydrochloride, Qsymia, Suprenza, phentermine hydrochloride
Warnings
Contraindicated in patients with "history of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension)," during or within 14 days of monoamine oxidase inhibitor use, hyperthyroidism, glaucoma, agitated states, a history of drug abuse, and in pregnancy/nursing. Key warnings: "rare cases of primary pulmonary hypertension have been reported" and "rare cases of serious regurgitant cardiac valvular disease have been reported"; "tolerance to the anorectic effect usually develops within a few weeks"; phentermine is a Schedule IV controlled substance with potential for abuse and dependence.
Uses
Phentermine hydrochloride is "indicated as a short-term adjunct (a few weeks) in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity" for patients with a BMI ≥30 kg/m², or ≥27 kg/m² "in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia)."
Dosage forms & strengths
All identified pills
R316
WHITE OVAL · Phentermine
U 48
YELLOW CAPSULE · Phentermine
2 manufacturers
U 47
GRAY;YELLOW CAPSULE · Phentermine
3 manufacturers
U40
WHITE CAPSULE · Phentermine
5 manufacturers
VIVUS 1125
YELLOW CAPSULE · Phentermine
VIVUS 15
YELLOW;WHITE CAPSULE · Phentermine
VIVUS 375
PURPLE CAPSULE · Phentermine
VIVUS 75
PURPLE;YELLOW CAPSULE · Phentermine
barr 30
ORANGE CAPSULE · Phentermine
barr 15
GRAY;YELLOW CAPSULE · Phentermine
Side effects
Reported reactions include cardiovascular effects (palpitation, tachycardia, elevated blood pressure); CNS effects (overstimulation, restlessness, dizziness, insomnia, tremor, headache); gastrointestinal effects ("dryness of the mouth, unpleasant taste, diarrhea, constipation"); and other effects including urticaria, impotence, and changes in libido.