Minocycline

Brand names: DYNACIN, Fish Min, MINOCYCLINE HYDROCHLORIDE, Minocin, Minocin Kit, Minocycline Hydrochloride, Minocycline hydrochloride, Minolira, Minolira Extended Release, Solodyn, Ximino, minocycline hydrochloride, ZILXI, AMZEEQ

Warnings

BOXED WARNING: "MINOCYCLINE HYDROCHLORIDE TABLETS, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN," with use during tooth development (last half of pregnancy through age 8) causing permanent tooth discoloration (yellow-gray-brown) and enamel hypoplasia. Other key warnings: photosensitivity reactions, CNS effects (dizziness, vertigo), Clostridium difficile-associated diarrhea (CDAD), Drug Rash with Eosinophilia and Systemic Symptoms (DRESS), and pseudotumor cerebri (benign intracranial hypertension), which can occur with concomitant isotretinoin and may cause permanent vision loss.

Contraindications

4 CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any other ingredients in ZILXI. This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any of the ingredients in ZILXI. ( 4 )

Drug interactions

7 DRUG INTERACTIONS • Patients on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. ( 7.1 ) • Penicillin: avoid coadministration. ( 7.2 ) 7.1 Anticoagulants Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. 7.2 Penicillin Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. 7.3 Drug/Laboratory Test Interactions False elevations of urinary catecholamine levels may occur due to interference with the fluorescence test.

Uses

Minocycline Hydrochloride Tablets are indicated for infections caused by susceptible organisms, including rickettsial infections (Rocky Mountain spotted fever, typhus fever, Q fever), respiratory tract infections due to Mycoplasma pneumoniae, sexually transmitted infections (chlamydia, uncomplicated gonorrhea, syphilis), skin/soft-tissue and urinary tract infections, and as adjunctive therapy in severe acne; it is also used to eliminate the meningococcal carrier state. As with other antibacterials, the label states minocycline "should be used to treat only infections that are proven or strongly suspected to be caused by susceptible bacteria."

Dosage forms & strengths

C42896 Capsule Capsule, Extended Release Tablet Tablet, Extended Release Tablet, Film Coated Tablet, Film Coated, Extended Release AEROSOL, FOAM POWDER

MINOCYCLINE HYDROCHLORIDE 1 mg MINOCYCLINE HYDROCHLORIDE 100 mg MINOCYCLINE HYDROCHLORIDE 105 mg MINOCYCLINE HYDROCHLORIDE 115 mg MINOCYCLINE HYDROCHLORIDE 135 mg MINOCYCLINE HYDROCHLORIDE 45 mg MINOCYCLINE HYDROCHLORIDE 50 mg MINOCYCLINE HYDROCHLORIDE 55 mg MINOCYCLINE HYDROCHLORIDE 65 mg MINOCYCLINE HYDROCHLORIDE 75 mg MINOCYCLINE HYDROCHLORIDE 80 mg MINOCYCLINE HYDROCHLORIDE 90 mg Minocycline Hydrochloride 100 mg Minocycline Hydrochloride 105 mg Minocycline Hydrochloride 135 mg Minocycline Hydrochloride 50 mg Minocycline Hydrochloride 75 mg minocycline hydrochloride 100 mg minocycline hydrochloride 105 mg minocycline hydrochloride 115 mg minocycline hydrochloride 135 mg minocycline hydrochloride 45 mg minocycline hydrochloride 50 mg minocycline hydrochloride 55 mg minocycline hydrochloride 65 mg minocycline hydrochloride 75 mg minocycline hydrochloride 80 mg minocycline hydrochloride 90 mg MINOCYCLINE HYDROCHLORIDE 15 mg/g MINOCYCLINE HYDROCHLORIDE 1 g/g MINOCYCLINE HYDROCHLORIDE 40 mg/g

2 DOSAGE AND ADMINISTRATION For topical use only, not for oral, ophthalmic or intravaginal use. After shaking the can well, a small amount of topical foam (e.g. a cherry-sized amount) should be expressed from the can onto the fingertips of the hand and then applied as a thin layer over all areas of the face. Additional ZILXI foam may be used as needed to ensure the entire face is treated. The topical foam should be applied at approximately the same time each day at least 1 hour before bedtime. The patient should not bathe, shower or swim for at least 1 hour after application of the product. Apply ZILXI over all areas of the face once daily. ZILXI should be gently rubbed into the skin. ( 2 )

Minocycline

Warnings

Contraindications

Drug interactions

Uses

Dosage forms & strengths

All identified pills

Side effects

Official source