Methocarbamol

Brand names: Methocarb 500-EZS, ROBAXIN, Robaxin, Methocarbamol, Methocarbamol Tablets, USP, 500 mg, methocarbamol, METHOCARBAMOL, Tanlor, Methocarbamol Tablets, USP, 750 mg, ATMEKSI

Warnings

No boxed warning. Contraindicated in patients "hypersensitive to methocarbamol or to any of the tablet components." Key warnings include additive CNS depression with "combined effects with alcohol and other CNS depressants"; a caution that "methocarbamol tablets USP should not be used in women who are or may become pregnant" due to reports of "fetal and congenital abnormalities"; and an instruction to avoid hazardous activities because the drug "may impair mental and/or physical abilities required for performance of hazardous tasks."

Contraindications

CONTRAINDICATIONS Methocarbamol tablets USP are contraindicated in patients hypersensitive to methocarbamol or to any of the tablet components.

Overdose

OVERDOSAGE Limited information is available on the acute toxicity of methocarbamol. Overdose of methocarbamol is frequently in conjunction with alcohol or other CNS depressants and includes the following symptoms: nausea, drowsiness, blurred vision, hypotension, seizures, and coma. In post-marketing experience, deaths have been reported with an overdose of methocarbamol alone or in the presence of other CNS depressants, alcohol or psychotropic drugs. Treatment Management of overdose includes symptomatic and supportive treatment. Supportive measures include maintenance of an adequate airway, monitoring urinary output and vital signs, and administration of intravenous fluids if necessary. The usefulness of hemodialysis in managing overdose is unknown.

Drug interactions

Drug Interactions See WARNINGS and PRECAUTIONS for interaction with CNS drugs and alcohol. Methocarbamol may inhibit the effect of pyridostigmine bromide. Therefore, methocarbamol should be used with caution in patients with myasthenia gravis receiving anticholinesterase agents.

Uses

Methocarbamol is "indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions." The label explicitly notes that "methocarbamol does not directly relax tense skeletal muscles in man."

Dosage forms & strengths

Tablet Tablet, Coated Tablet, Film Coated TABLET TABLET, COATED POWDER TABLET, FILM COATED INJECTION INJECTION, SOLUTION KIT SUSPENSION

METHOCARBAMOL 500 mg METHOCARBAMOL 750 mg Methocarbamol 500 mg Methocarbamol 750 mg METHOCARBAMOL 750 mg/1 METHOCARBAMOL 500 mg/1 METHOCARBAMOL 1000 mg/1 METHOCARBAMOL 1 kg/kg METHOCARBAMOL 50 kg/50kg METHOCARBAMOL 100 mg/mL METHOCARBAMOL 1000 mg/10mL METHOCARBAMOL 1 g/g METHOCARBAMOL 750 mg/5mL

DOSAGE & ADMINISTRATION Methocarbamol Tablets USP 500 mg – Adults: Initial dosage: 3 tablets q.i.d. Maintenance dosage: 2 tablets q.i.d. Methocarbamol Tablets USP 750 mg – Adults: Initial dosage: 2 tablets q.i.d. Maintenance dosage: 1 tablet q.4h. or 2 tablets t.i.d. Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be reduced to approximately 4 grams a day.

All identified pills

114 H

WHITE OVAL · Methocarbamol

24 manufacturers

115 H

WHITE OVAL · Methocarbamol

32 manufacturers

4211 V

WHITE ROUND · Methocarbamol

21 manufacturers

4212 V

WHITE OVAL · Methocarbamol

20 manufacturers

Methocarbamol

Warnings

Contraindications

Overdose

Drug interactions

Uses

Dosage forms & strengths

All identified pills

Side effects

Official source