Levothyroxine
Brand names: LEVO-T, LEVOXYL, Levothyroxine Sodium, Levothyroxine sodium, Synthroid
Warnings
BOXED WARNING: "Thyroid hormones should not be used for the treatment of obesity or for weight loss. Larger doses may produce serious or even life threatening manifestations of toxicity." Major Warnings: - Cardiac risks: "Over-treatment may cause an increase in heart rate, cardiac wall thickness, and cardiac contractility and may precipitate angina or arrhythmias"—especially in elderly and cardiac disease patients - Myxedema coma: Do not use oral products; requires intravenous administration - Adrenal crisis: Treat adrenal insufficiency with glucocorticoids before initiating therapy - Narrow therapeutic index: Risk of adverse effects on growth, cardiac function, metabolism, and cognitive function from over/undertreatment - Diabetic control: May "worsen glycemic control and result in increased antidiabetic agent or insulin requirements" - Bone density: Over-replacement increases bone resorption ---
Uses
Levothyroxine sodium tablets are indicated for: - Hypothyroidism: "replacement therapy in primary (thyroidal), secondary (pituitary) and tertiary (hypothalamic) congenital or acquired hypothyroidism" - TSH Suppression: "as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer" Limitations: Not for benign thyroid nodules/nontoxic goiter in iodine-sufficient patients or hypothyroidism during recovery from subacute thyroiditis. ---
Dosage forms & strengths
All identified pills
M L
GRAY CAPSULE · Levothyroxine
2 manufacturers
M L
TURQUOISE CAPSULE · Levothyroxine
M L
PINK OVAL · Levothyroxine
2 manufacturers
M L
PINK OVAL · Levothyroxine
M L
ORANGE OVAL · Levothyroxine
5 manufacturers
M L
GREEN OVAL · Levothyroxine
M L
GREEN OVAL · Levothyroxine
4 manufacturers
M L
WHITE OVAL · Levothyroxine
5 manufacturers
M L
YELLOW OVAL · Levothyroxine
7 manufacturers
M L
BLUE OVAL · Levothyroxine
5 manufacturers
M L
RED OVAL · Levothyroxine
M
BROWN OVAL · Levothyroxine
2 manufacturers
M L
PURPLE OVAL · Levothyroxine
3 manufacturers
M L
PURPLE OVAL · Levothyroxine
5 manufacturers
M L
GRAY OVAL · Levothyroxine
4 manufacturers
M L
TURQUOISE OVAL · Levothyroxine
3 manufacturers
N
BROWN OVAL · Levothyroxine
2 manufacturers
P
BROWN OVAL · Levothyroxine
2 manufacturers
S
BROWN OVAL · Levothyroxine
2 manufacturers
SYNTHROID 200
PINK ROUND · Levothyroxine
5 manufacturers
SYNTHROID 25
ORANGE ROUND · Levothyroxine
8 manufacturers
SYNTHROID 300
GREEN ROUND · Levothyroxine
3 manufacturers
SYNTHROID 88
GREEN ROUND · Levothyroxine
8 manufacturers
SYNTHROID 50
WHITE ROUND · Levothyroxine
SYNTHROID 50
WHITE ROUND · Levothyroxine
7 manufacturers
SYNTHROID 100
YELLOW ROUND · Levothyroxine
8 manufacturers
SYNTHROID 150
BLUE ROUND · Levothyroxine
SYNTHROID 137
BLUE ROUND · Levothyroxine
5 manufacturers
SYNTHROID 150
BLUE ROUND · Levothyroxine
8 manufacturers
SYNTHROID 112
RED ROUND · Levothyroxine
5 manufacturers
SYNTHROID 125
BROWN ROUND · Levothyroxine
7 manufacturers
SYNTHROID 175
PURPLE ROUND · Levothyroxine
5 manufacturers
SYNTHROID 75
PURPLE ROUND · Levothyroxine
9 manufacturers
U
BROWN OVAL · Levothyroxine
2 manufacturers
WP 155
BROWN ROUND · Levothyroxine
2 manufacturers
WP 156
BROWN ROUND · Levothyroxine
2 manufacturers
WP 157
BROWN ROUND · Levothyroxine
WP 158
BROWN ROUND · Levothyroxine
WP 159
BROWN ROUND · Levothyroxine
Y
BROWN OVAL · Levothyroxine
2 manufacturers
YC
PURPLE;WHITE ROUND · Levothyroxine
YD
ORANGE;WHITE ROUND · Levothyroxine
YE
PINK;WHITE ROUND · Levothyroxine
YF
GREEN;WHITE ROUND · Levothyroxine
YH
YELLOW;WHITE ROUND · Levothyroxine
dp 200
PINK OVAL · Levothyroxine
dp 112
PINK OVAL · Levothyroxine
dp 200
PINK OVAL · Levothyroxine
Side effects
Adverse reactions primarily result from "hyperthyroidism due to therapeutic overdosage" and include: - General: fatigue, weight loss, heat intolerance, fever, excessive sweating - CNS: headache, nervousness, anxiety, insomnia, tremors - Cardiovascular: palpitations, tachycardia, arrhythmias, angina, myocardial infarction - GI: diarrhea, vomiting, abdominal cramps - Other: muscle weakness, dyspnea, hair loss, menstrual irregularities In children: pseudotumor cerebri and slipped capital femoral epiphysis reported ---