Levothyroxine
Brand names: LEVO-T, LEVOXYL, Levothyroxine Sodium, Levothyroxine sodium, Synthroid
Warnings
BOXED WARNING: "Thyroid hormones should not be used for the treatment of obesity or for weight loss. Larger doses may produce serious or even life threatening manifestations of toxicity." Major Warnings: - Cardiac risks: "Over-treatment may cause an increase in heart rate, cardiac wall thickness, and cardiac contractility and may precipitate angina or arrhythmias"—especially in elderly and cardiac disease patients - Myxedema coma: Do not use oral products; requires intravenous administration - Adrenal crisis: Treat adrenal insufficiency with glucocorticoids before initiating therapy - Narrow therapeutic index: Risk of adverse effects on growth, cardiac function, metabolism, and cognitive function from over/undertreatment - Diabetic control: May "worsen glycemic control and result in increased antidiabetic agent or insulin requirements" - Bone density: Over-replacement increases bone resorption ---
Uses
Levothyroxine sodium tablets are indicated for: - Hypothyroidism: "replacement therapy in primary (thyroidal), secondary (pituitary) and tertiary (hypothalamic) congenital or acquired hypothyroidism" - TSH Suppression: "as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer" Limitations: Not for benign thyroid nodules/nontoxic goiter in iodine-sufficient patients or hypothyroidism during recovery from subacute thyroiditis. ---
Dosage forms & strengths
All identified pills
137 GG
TURQUOISE CAPSULE · Levothyroxine
2 manufacturers
137
BLUE ROUND · Levothyroxine
137 GG
GREEN OVAL · Levothyroxine
137 T4
BLUE OVAL · Levothyroxine
137 GG
GREEN BULLET · Levothyroxine
2 manufacturers
150 GG
BLUE CAPSULE · Levothyroxine
20 manufacturers
150
BLUE ROUND · Levothyroxine
150 GG338
BLUE OVAL · Levothyroxine
150 T4
BLUE OVAL · Levothyroxine
2 manufacturers
150 GG
BLUE BULLET · Levothyroxine
3 manufacturers
175 GG
PURPLE CAPSULE · Levothyroxine
11 manufacturers
175 GG
PURPLE CAPSULE · Levothyroxine
175
PURPLE ROUND · Levothyroxine
175 T4
PURPLE OVAL · Levothyroxine
2 manufacturers
200 GG
PINK CAPSULE · Levothyroxine
11 manufacturers
200
PINK ROUND · Levothyroxine
200 GG
PINK OVAL · Levothyroxine
2 manufacturers
200 T4
PINK OVAL · Levothyroxine
2 manufacturers
25 GG
ORANGE CAPSULE · Levothyroxine
18 manufacturers
25
ORANGE ROUND · Levothyroxine
25 GG
ORANGE OVAL · Levothyroxine
25 T4
ORANGE OVAL · Levothyroxine
25 GG
ORANGE BULLET · Levothyroxine
2 manufacturers
300 GG
GREEN CAPSULE · Levothyroxine
4 manufacturers
300 T4
GREEN OVAL · Levothyroxine
50 GG
WHITE CAPSULE · Levothyroxine
50 GG
WHITE CAPSULE · Levothyroxine
26 manufacturers
50
WHITE ROUND · Levothyroxine
50 T4
WHITE OVAL · Levothyroxine
3 manufacturers
50 GG
WHITE BULLET · Levothyroxine
2 manufacturers
75 GG
BLUE CAPSULE · Levothyroxine
75 GG
BLUE CAPSULE · Levothyroxine
75 GG
PURPLE CAPSULE · Levothyroxine
24 manufacturers
75
PURPLE ROUND · Levothyroxine
75 T4
PURPLE OVAL · Levothyroxine
3 manufacturers
75 GG
PURPLE BULLET · Levothyroxine
88 GG
GREEN CAPSULE · Levothyroxine
17 manufacturers
88
GREEN ROUND · Levothyroxine
88 T4
GREEN OVAL · Levothyroxine
2 manufacturers
A
BROWN OVAL · Levothyroxine
2 manufacturers
AP 329
BROWN ROUND · Levothyroxine
7 manufacturers
AP 330
BROWN ROUND · Levothyroxine
AP 330
BROWN ROUND · Levothyroxine
6 manufacturers
AP 331
BROWN ROUND · Levothyroxine
6 manufacturers
AP 328
BROWN ROUND · Levothyroxine
2 manufacturers
AP 327
BROWN ROUND · Levothyroxine
2 manufacturers
E
BROWN OVAL · Levothyroxine
2 manufacturers
EM 100
WHITE ROUND · Levothyroxine
Side effects
Adverse reactions primarily result from "hyperthyroidism due to therapeutic overdosage" and include: - General: fatigue, weight loss, heat intolerance, fever, excessive sweating - CNS: headache, nervousness, anxiety, insomnia, tremors - Cardiovascular: palpitations, tachycardia, arrhythmias, angina, myocardial infarction - GI: diarrhea, vomiting, abdominal cramps - Other: muscle weakness, dyspnea, hair loss, menstrual irregularities In children: pseudotumor cerebri and slipped capital femoral epiphysis reported ---