Donepezil

Brand names: Aricept, DONEPEZIL HYDROCHLORIDE, Donepezil Hydrochloride, Donepezil Hyrochloride, Donepezil hydrochloride, donepezil hydrochloride

Warnings

Contraindicated in patients with "known hypersensitivity to donepezil hydrochloride or to piperidine derivatives." Key warnings: as a cholinesterase inhibitor, it is "likely to exaggerate succinylcholine-type muscle relaxation during anesthesia"; may have "vagotonic effects on the sinoatrial and atrioventricular nodes manifesting as bradycardia or heart block"; "ARICEPT can cause vomiting," with an associated risk of gastrointestinal bleeding, particularly at higher doses; weight loss has been reported with the 23 mg dose; potential to cause seizures in susceptible patients.

Uses

ARICEPT (donepezil hydrochloride) "is indicated for the treatment of dementia of the Alzheimer's type. Efficacy has been demonstrated in patients with mild, moderate, and severe Alzheimer's disease."

Dosage forms & strengths

Tablet Tablet, Extended Release Tablet, Film Coated Tablet, Orally Disintegrating POWDER

DONEPEZIL HYDROCHLORIDE 10 mg DONEPEZIL HYDROCHLORIDE 23 mg DONEPEZIL HYDROCHLORIDE 5 mg Donepezil Hydrochloride 10 mg Donepezil Hydrochloride 23 mg Donepezil Hydrochloride 5 mg donepezil hydrochloride 10 mg donepezil hydrochloride 5 mg DONEPEZIL HYDROCHLORIDE 5 kg/5kg