Clindamycin
Brand names: Antirobe, Cleocin Hydrochloride, Clindamycin Hydrochloride, Clindamycin hydrochloride, clindamycin hydrochloride, Clindagel
Warnings
Boxed Warning: Clostridium difficile-associated diarrhea (CDAD) ranging from mild diarrhea to fatal colitis has been reported. The drug alters normal colon flora, risking C. difficile overgrowth. "CDAD must be considered in all patients who present with diarrhea following antibiotic use," even occurring over two months after therapy ends. Additional warnings include severe skin reactions (including fatal cases), contraindication in meningitis (inadequate CSF penetration), and caution in patients with gastrointestinal disease or hepatic/renal impairment.
Contraindications
CONTRAINDICATIONS CLINDAGEL is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
Overdose
OVERDOSAGE Topically applied CLINDAGEL may be absorbed in sufficient amounts to produce systemic effects (see WARNINGS ).
Uses
Clindamycin treats serious infections caused by susceptible bacteria, including anaerobes, streptococci, pneumococci, and staphylococci. Use should be reserved for penicillin-allergic patients or when penicillin is inappropriate. Specific indications include respiratory tract infections, skin and soft tissue infections, septicemia, intra-abdominal infections, and pelvic/genital infections. "Bacteriologic studies should be performed to determine the causative organisms and their susceptibility."
Dosage forms & strengths
DOSAGE AND ADMINISTRATION Apply a thin film of CLINDAGEL once daily to the skin where acne lesions appear. Use enough to cover the entire affected area lightly. Keep container tightly closed.
All identified pills
ANTIROBE 75
GREEN CAPSULE · Clindamycin
2 manufacturers
ANTIROBE 300
BLUE CAPSULE · Clindamycin
ANTIROBE 25
YELLOW;WHITE CAPSULE · Clindamycin
2 manufacturers
ANTIROBE 150
BLUE;GREEN CAPSULE · Clindamycin
2 manufacturers
C 39
BLUE CAPSULE · Clindamycin
4 manufacturers
C 40
BLUE CAPSULE · Clindamycin
14 manufacturers
C 39
BLUE;GREEN CAPSULE · Clindamycin
8 manufacturers
C 25
WHITE ROUND · Clindamycin
C150
WHITE ROUND · Clindamycin
C25
WHITE ROUND · Clindamycin
C75
WHITE ROUND · Clindamycin
CRONUS CLIN75
GREEN CAPSULE · Clindamycin
CRONUS CLIN25
YELLOW CAPSULE · Clindamycin
CRONUS CLIN150
BLUE CAPSULE · Clindamycin
CRONUS CLIN300
TURQUOISE CAPSULE · Clindamycin
Cleocin 75
GREEN CAPSULE · Clindamycin
Cleocin 300
BLUE CAPSULE · Clindamycin
Cleocin 150
BLUE;GREEN CAPSULE · Clindamycin
DAN 3120
PINK CAPSULE · Clindamycin
20 manufacturers
DAN 5708
GRAY;PINK CAPSULE · Clindamycin
22 manufacturers
DAN 5708
PINK;GRAY CAPSULE · Clindamycin
G150 mg
BLUE;GREEN CAPSULE · Clindamycin
2 manufacturers
G300 mg
BLUE CAPSULE · Clindamycin
2 manufacturers
GW 5256
BLUE CAPSULE · Clindamycin
6 manufacturers
GW 3171
RED;BLUE CAPSULE · Clindamycin
2 manufacturers
GW 3171
BLUE;RED CAPSULE · Clindamycin
Lannett 1381
GREEN CAPSULE · Clindamycin
Lannett 1383
BLUE CAPSULE · Clindamycin
14 manufacturers
Lannett 1382
BLUE;GREEN CAPSULE · Clindamycin
7 manufacturers
M 40
GREEN CAPSULE · Clindamycin
M 42
BLUE CAPSULE · Clindamycin
5 manufacturers
M 41
GREEN;BLUE CAPSULE · Clindamycin
6 manufacturers
MYLAN CL
GREEN CAPSULE · Clindamycin
MYLAN CL
PURPLE CAPSULE · Clindamycin
MYLAN CL
PURPLE;GREEN CAPSULE · Clindamycin
Ml 42
BLUE CAPSULE · Clindamycin
4 manufacturers
RX692
BLUE CAPSULE · Clindamycin
RX692
TURQUOISE CAPSULE · Clindamycin
2 manufacturers
RX692
BLUE;GREEN CAPSULE · Clindamycin
RX692
BLUE;GREEN CAPSULE · Clindamycin
33 manufacturers
RX692
GREEN;BLUE CAPSULE · Clindamycin
3 manufacturers
RX693
BLUE CAPSULE · Clindamycin
3 manufacturers
RX693
BLUE;BLUE CAPSULE · Clindamycin
22 manufacturers
TEVA 5256
BLUE CAPSULE · Clindamycin
3 manufacturers
TEVA 3171
RED CAPSULE · Clindamycin
TEVA 3171
RED;BLUE CAPSULE · Clindamycin
3 manufacturers
Z 90
BLUE;BLUE CAPSULE · Clindamycin
2 manufacturers
Z 91
BLUE;BLUE CAPSULE · Clindamycin
2 manufacturers
Side effects
Most frequent adverse reactions are mild-to-moderate skin rashes. Other reported effects include gastrointestinal symptoms (abdominal pain, nausea, vomiting, diarrhea), pseudomembranous colitis, hypersensitivity reactions, and rare severe reactions like Stevens-Johnson syndrome.