Benazepril
Brand names: BENAZEPRIL HYDROCHLORIDE, Benazepril HCl, Benazepril Hydrochloride, Benazepril hydrochloride, Lotensin, benazepril hydrochloride
Warnings
BOXED WARNING: Fetal toxicity - "When pregnancy is detected, discontinue benazepril as soon as possible," because ACE inhibitors used during the second and third trimesters can cause fetal injury and death. Other key warnings include angioedema (facial, lingual, or laryngeal swelling with potential airway obstruction, requiring immediate discontinuation), contraindication in patients with a history of ACE-inhibitor-associated angioedema or concomitant use with neprilysin inhibitors (e.g., sacubitril), hyperkalemia risk especially with potassium-sparing diuretics, worsening renal function, and symptomatic hypotension.
Uses
Benazepril Hydrochloride Tablets are "indicated for the treatment of hypertension, to lower blood pressure." Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. It may be used alone or combined with other antihypertensive agents.
Dosage forms & strengths
All identified pills
M 443
WHITE ROUND · Benazepril
3 manufacturers
M 444
WHITE ROUND · Benazepril
3 manufacturers
M 441
WHITE ROUND · Benazepril
M 447
WHITE OVAL · Benazepril
RX736
YELLOW ROUND · Benazepril
RX737
YELLOW ROUND · Benazepril
RX738
PINK ROUND · Benazepril
RX739
PINK ROUND · Benazepril
S 341
WHITE ROUND · Benazepril
6 manufacturers
S 344
BLUE ROUND · Benazepril
15 manufacturers
S 342
RED ROUND · Benazepril
16 manufacturers
S 343
GRAY ROUND · Benazepril
21 manufacturers
Side effects
Common adverse reactions reported include headache (about 6%), dizziness (about 4%), and cough, which led to discontinuation in about 0.5% of patients. Less common but serious reactions include angioedema, Stevens-Johnson syndrome, hepatic necrosis, thrombocytopenia, hemolytic anemia, and acute renal failure.