Atorvastatin
Brand names: ATORVASTATIN CALCIUM, Atorvastatin Calcium, Lipitor
Warnings
Key warnings include: - Myopathy/Rhabdomyolysis: Risk factors include age ≥65 years, uncontrolled hypothyroidism, renal impairment, concomitant drugs, and higher doses. "Discontinue atorvastatin calcium if markedly elevated CK levels occur or myopathy is diagnosed or suspected." - Immune-Mediated Necrotizing Myopathy (IMNM): Rare autoimmune myopathy reported with statins; discontinue if suspected. - Hepatic Dysfunction: Transaminase increases reported; contraindicated in acute liver failure or decompensated cirrhosis. "If serious hepatic injury with clinical symptoms...occurs, promptly discontinue." - HbA1c/Glucose: Increases in blood sugar levels reported. - Hemorrhagic Stroke Risk: Increased hemorrhagic stroke incidence at 80 mg dose in patients with recent hemorrhagic stroke.
Uses
Atorvastatin calcium tablets are indicated to: - Reduce risk of MI, stroke, revascularization procedures, and angina in adults with multiple CHD risk factors but without clinically evident CHD - Reduce risk of MI and stroke in adults with type 2 diabetes with CHD risk factors - Reduce risk of non-fatal MI, fatal/non-fatal stroke, revascularization, heart failure hospitalization, and angina in adults with clinically evident CHD - As adjunct to diet to reduce LDL-C in adults and pediatric patients (age 10+) with primary hyperlipidemia and familial hypercholesterolemia - Treat adults with primary dysbetalipoproteinemia and hypertriglyceridemia
Dosage forms & strengths
All identified pills
1
WHITE ROUND · Atorvastatin
4 manufacturers
1
WHITE ROUND · Atorvastatin
18 manufacturers
10
WHITE OVAL · Atorvastatin
8 manufacturers
11
WHITE OVAL · Atorvastatin
2 manufacturers
114
WHITE OVAL · Atorvastatin
3 manufacturers
115
WHITE OVAL · Atorvastatin
2 manufacturers
116
WHITE OVAL · Atorvastatin
2 manufacturers
2
WHITE ROUND · Atorvastatin
5 manufacturers
2
WHITE ROUND · Atorvastatin
13 manufacturers
20
WHITE OVAL · Atorvastatin
8 manufacturers
249
WHITE OVAL · Atorvastatin
3 manufacturers
250
WHITE OVAL · Atorvastatin
3 manufacturers
251
WHITE OVAL · Atorvastatin
3 manufacturers
252
WHITE OVAL · Atorvastatin
3 manufacturers
320
WHITE OVAL · Atorvastatin
321
WHITE ROUND · Atorvastatin
322
WHITE OVAL · Atorvastatin
323
WHITE OVAL · Atorvastatin
40
WHITE ROUND · Atorvastatin
6 manufacturers
40
WHITE ROUND · Atorvastatin
11 manufacturers
40
WHITE OVAL · Atorvastatin
11 manufacturers
80
WHITE ROUND · Atorvastatin
4 manufacturers
80
WHITE ROUND · Atorvastatin
8 manufacturers
80
WHITE OVAL · Atorvastatin
80
WHITE OVAL · Atorvastatin
8 manufacturers
APO A10
WHITE OVAL · Atorvastatin
5 manufacturers
APO ATV20
WHITE OVAL · Atorvastatin
9 manufacturers
APO ATV40
WHITE OVAL · Atorvastatin
7 manufacturers
APO ATV80
WHITE OVAL · Atorvastatin
6 manufacturers
APO A10
WHITE OVAL · Atorvastatin
9 manufacturers
APO ATV20
WHITE OVAL · Atorvastatin
8 manufacturers
APO ATV40
WHITE OVAL · Atorvastatin
10 manufacturers
APO ATV80
WHITE OVAL · Atorvastatin
7 manufacturers
APO A10
WHITE OVAL · Atorvastatin
20 manufacturers
APO ATV20
WHITE OVAL · Atorvastatin
21 manufacturers
APO ATV40
WHITE OVAL · Atorvastatin
22 manufacturers
APO ATV80
WHITE OVAL · Atorvastatin
16 manufacturers
ATO 10
WHITE OVAL · Atorvastatin
ATO 20
WHITE OVAL · Atorvastatin
ATO 40
WHITE OVAL · Atorvastatin
ATO 80
WHITE OVAL · Atorvastatin
FF1
WHITE OVAL · Atorvastatin
7 manufacturers
FF2
WHITE OVAL · Atorvastatin
8 manufacturers
FF3
WHITE OVAL · Atorvastatin
3 manufacturers
FF4
WHITE OVAL · Atorvastatin
2 manufacturers
HLA 10
YELLOW ROUND · Atorvastatin
HLA 20
YELLOW ROUND · Atorvastatin
HLA 10
YELLOW ROUND · Atorvastatin
Side effects
Most common adverse reactions (≥5%) from clinical trials: - Nasopharyngitis - Arthralgia - Diarrhea - Pain in extremity - Urinary tract infection Other notable reactions: dyspepsia, nausea, musculoskeletal pain, muscle spasms, myalgia, insomnia, and pharyngeal pain. Postmarketing reports include rhabdomyolysis, hepatic failure, cognitive impairment, interstitial lung disease, and severe skin reactions.